Showing posts with label Ebola. Show all posts
Showing posts with label Ebola. Show all posts

Tuesday, 17 December 2013

Online catalogue of Peter Piot's archives now available

The archive collection of Professor Baron Peter Piot is now available online on the archive catalogue. The papers held at the School reflect his career in fighting epidemic disease not only through his epidemiological work on the Ebola virus and HIV/AIDS but also his role as Executive-Director of UNAIDS (1995-2008).



Peter Piot 

Baron Professor Peter Karcl Piot, was born on the 17th February 1949 in Louvain, Belgium. He studied medicine at the University of Ghent (achieving his M.D. in 1974) and after graduation moved to the Institute of Tropical Medicine, Antwerp, to work under Dr S. R. Pattyn. In 1976, he and his colleague, Guido van der Groen, were chosen from the School to join the WHO International Commission investigating the then unknown Ebola virus in Zaire (now Democratic Republic of Congo), having been part of the team that had isolated the virus.

In 1980 he received his PhD in microbiology and became Associate Professor of Microbiology and Head of the Division of Microbiology at the Institute. Based in Antwerp, he set up a number of international projects in Africa chiefly looking at the spread of the HIV/AIDS on the continent. In 1983, he helped establish the international project based in Kinshasa, known as Projet SIDA that was the initial source of epidemiological work on HIV/AIDS in Africa. Between 1986-1987 he became an Associate Professor, Department of Medical Microbiology at the University of Nairobi, Kenya.

The following year, he became chair of the Steering Committee on Epidemiology and Surveillance of WHO's Global Programme on AIDS. In 1991 he was elected President of the International AIDS Society and then left his position in Antwerp to move to Geneva to become an Associate Director of the Global Programme on AIDS, World Health Organisation. In 1995, he was elected Executive-Director of  the Joint United Nations Programme on HIV/AIDS (UNAIDS) and served in this position for thirteen years before leaving in 2008 to become Professor of Global Health, Imperial College London. In 2010, he was appointed Director of the London School of Hygiene and Tropical Medicine.


Archives

The papers held at the School reflect his career in fighting disease with fieldwork based on his epidemiological work on the Ebola virus and HIV/AIDS in Kinshasa. Correspondence files from his time as Professor of Microbiology in Antwerp provide an insight on the international network of medical experts working on the AIDS pandemic in the 1980's with conference papers on notable meetings such as the first African meeting on AIDS in Bangui, 1985. 

The majority of the papers in the collection relate to his tenure of Executive-Director of UNAIDS. The papers incorporate material relating to the establishment and governance of the organisation and also the working life of the Executive-Director through his speeches; correspondence; conferences; meeting notes; travel documents and also hold a rich source of working papers on significant developments in his tenure such as the South African AIDS epidemic; the formation of the Global Fund against AIDS, Tuberculosis and Malaria and the United State's
President's Emergency Plan for AIDS Relief (PEPFAR). Papers also include collected articles, newspaper articles and reports relating to Piot's career and various topics relating to the global strategy for the prevention of HIV/AIDS.

The collection can be viewed by appointment by contacting the archive service by email at the following address, Archives@lshtm.ac.uk.

Wednesday, 16 October 2013

Peter Piot and the Ebola outbreak in the Yambuku in 1976




Within the archives of Peter Piot, surrounded by decades of material surrounding HIV/AIDS was a small box file, simply entailed, ‘Ebola’. Within it were papers relating to his work with the International Medical Commission in Zaire (now Democratic Republic of Congo) to investigate an unknown hemorrhagic fever that erupted spontaneously in 1976. The disease infected 318 people, killing 280 people in a two month period. It’s lethalness was only rivalled by that of rabies and spread widespread fear across the region. As a junior member of the Department of Microbiology Department at the Institute of Tropical Medicine, Antwerp, Peter Piot’s life and career was dramatically affected by the emergence of this terrifying epidemic.

Newspaper cutting of the ITM team with Guido van der Groen, Peter Piot and Dr Stefaan Pattyn


The story of Piot’s involvement is comprehensively told in his memoir, No Time to Lose, but his archives convey the scope of his epidemiological work within the Yambuku region. Piot became a member of the International Medical Commission after the he and his colleagues at the ITM had identified a new virus from the blood samples taken from the Flemish nun who had caught the disease. What is truly terrifying about the account is the lack of precautions that were taken with the highly infectious blood from it turning up, semi-thawed in a thermos couriered on a passenger airline to the almost accidental contamination of one of his colleagues when a test tube of the virus smashed onto the floor and covered the shoes of his colleague, Rene Delgadillo. 


Electron microscope image of the Ebola virus

 
 
The alarming reports from Zaire along with the identifying a lethal new virus caused the World Health Organisation to mobilise an International Commission to investigate and contain the outbreak. Members of the ITM were drafted in to go to Kinshasa and Piot was one of them. He was a relative novice at the time and had not been to Africa nor even had a valid passport (having cut out the picture for a squash membership card). However, he leapt at the opportunity to go and reached Kinshasa on October 18th. President Mobutu Sese Seko had ordered the entire Bamba region to be quarantined and there was no information from the region regarding the severity of the epidemic. It was agreed that a small expeditionary team would go in and investigate; Peter Piot volunteered to be on it.


The archives note the epidemiological procedures the expeditionary party took during this period. Using they’re airlifted land rovers to visit local hospital and affected villages the team same came to some preliminary conclusions about the epidemic. Firstly, the peak of the epidemic had already been reached and the team could not identify any new cases; the main source of transmission was hypothesized and later proved to be the Yambuku hospital ran by the Flemish nuns, unwittingly the hospital staff had passed on the infection to a host of people through the re-use of syringes; whilst other cases seemed to be skin to skin transmission especially through preparation of the dead, the initial vector of the disease was not identified.

 
Map of the villages visited in the Yambuku region (1976)


On hearing the news, the international commission departed to the region to carry out more extensive epidemiological search and be certain that the disease was no longer a threat. Despite killing 88% of its victims the disease magnitude was deceased thanks to village elders imposing their own cordon sanitaire measures to prevent the spread of disease to surrounding areas and local people realising that the hospitals were the major source of the infection.


The experience with the Ebola virus had quite a transformative effect on Peter Piot’s life. Along with being grateful to being alive, he felt vindicated in his decision to pursue epidemic disease and eager to advance in his profession and shortly afterwards moved to America.